Neural injections of Bromodeoxyuridine (BrdU) were applied to males of both groups to test for neurogenesis . Analysis showed that testosterone and dihydrotestosterone regulated adult hippocampal neurogenesis (AHN). Adult hippocampal neurogenesis was regulated through the androgen receptor in the wild-type male rats, but not in the TMF male rats. To further test the role of activated androgen receptors on AHN, flutamide , an antiandrogen drug that competes with testosterone and dihydrotestosterone for androgen receptors , and dihydrotestosterone were administered to normal male rats. Dihydrotestosterone increased the number of BrdU cells, while flutamide inhibited these cells.
Boldenon should be considered only as adjunctive therapy to other specific and supportive therapy for diseases, surgical cases and traumatic injuries.
Boldenon 200 USP injection provides boldenone cypionate is a long acting anabolic steroid used in veterinary medicine for the treatment of horses. Boldenon possess marked anabolic properties and a minimal amount of androgenic activity. Boldenon has a rapid onset of action; this is advantageous and is preferred over frequent oral dosing or even repeated injections. The esterification of the 17-beta-hydroxyl group increases the duration of the action of boldenon . Boldenon esters in oil injected intramuscularly are absorbed slowly from the lipid phase, thus Boldenon 200 can be administered at intervals of every 2-3 weeks.