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Excessive decrease in blood pressure; patients with hypovolemia and hyponatremia
Irbesartan rarely cause an excessive fall in blood pressure in hypertensive patients without other comorbidities. As well as taking ACE inhibitors, may be expected to excessive reduction of blood pressure with the corresponding symptoms in patients with hypovolemia and hyponatremia, which include patients undergoing intensive diuretic therapy, and / or patients with limited consumption of salt or patients undergoing hemodialysis. Hyponatremia and hypovolemia should be corrected before treatment with Aprovask ® or should consider the use of lower initial doses.