Testosterone and puberty

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Testosterone is a hormone produced in the male testes. During a boy's pubescent years (ages 9 to 14), there is an increase in production that leads to male secondary sexual characteristics such as a deeper voice, more muscle mass, facial hair growth and enlargement of the Adam's apple (among others). Some teenage boys experience these puberty changes at later ages than others. The timing of puberty is often genetically determined (through heredity), but other factors can play a role in delaying it, such as poor nutrition, physical trauma and certain diseases. Stimulating testosterone production naturally is possible in teen boys, although in rare cases hormone therapy may be needed to trigger and complete puberty.

Information from the Nurses' Health Study indicated that the combination of estrogen and androgen used to treat hypoandrogenism could increase breast cancer risk. However, other studies indicated androgens may decrease breast cancer risk. Follow-up studies on the Women's Health Initiative found women who received estrogen and no progestogen showed a significant decrease in cardiovascular disease (CVD) and breast cancer. This has caused a reconsideration of androgens added to estrogens. Still, the FDA requires demonstration of CVD and breast cancer safety for any product containing androgens or estrogen plus an androgen; that has not been done.

Other side effects include increased risk of heart problems in older men with poor mobility, according to a 2009 study at Boston Medical Center. A 2017 study published in JAMA found that treatments increase coronary artery plaque volume. Additionally, the Food and Drug Administration (FDA) requires manufactures to include a notice on the labeling that states taking testosterone treatments can lead to possible increased risk of heart attacks and strokes. The FDA recommends that patients using testosterone should seek medical attention right away if they have these symptoms:

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Testosterone and puberty

testosterone and puberty

Other side effects include increased risk of heart problems in older men with poor mobility, according to a 2009 study at Boston Medical Center. A 2017 study published in JAMA found that treatments increase coronary artery plaque volume. Additionally, the Food and Drug Administration (FDA) requires manufactures to include a notice on the labeling that states taking testosterone treatments can lead to possible increased risk of heart attacks and strokes. The FDA recommends that patients using testosterone should seek medical attention right away if they have these symptoms:

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